Novel 5-HT5A receptor antagonists ameliorate scopolamine-induced working memory deficit in mice and reference memory impairment in aged rats

• मुख्य लेखकों: Mayako Yamazaki (लेखक), Mayuko Okabe (लेखक), Noriyuki Yamamoto (लेखक), Junko Yarimizu (लेखक), Katsuya Harada (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2015-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Despite the human 5-HT5A receptor being cloned in 1994, the biological function of this receptor has not been extensively characterized due to a lack of specific ligands. We recently reported that the selective 5-HT5A receptor antagonist ASP5736 ameliorated cognitive impairment in several animal mod...