Polydopamine-Modified Copper Coordination Mesoporous Silica Nanoparticles Loaded with Disulfiram for Synergistic Chemo-Photothermal Therapy

Disulfiram (DSF) degrades to diethyldithiocarbamate (DTC) in vivo and coordinates with copper ions to form CuET, which has higher antitumor activity. In this study, DSF@CuMSN-PDA nanoparticles were prepared using mesoporous silica with copper ions, DSF as a carrier, and polydopamine (PDA) as a gate...

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Main Authors: Junhong Ling (Author), Yingying Cai (Author), Haozhan Feng (Author), Zhen Liu (Author), Xiao-kun Ouyang (Author)
Format: Book
Published: MDPI AG, 2024-04-01T00:00:00Z.
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