Polydopamine-Modified Copper Coordination Mesoporous Silica Nanoparticles Loaded with Disulfiram for Synergistic Chemo-Photothermal Therapy

• Príomhchruthaitheoirí: Junhong Ling (Údar), Yingying Cai (Údar), Haozhan Feng (Údar), Zhen Liu (Údar), Xiao-kun Ouyang (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2024-04-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Disulfiram (DSF) degrades to diethyldithiocarbamate (DTC) in vivo and coordinates with copper ions to form CuET, which has higher antitumor activity. In this study, DSF@CuMSN-PDA nanoparticles were prepared using mesoporous silica with copper ions, DSF as a carrier, and polydopamine (PDA) as a gate...