Initial Characterization of Stressed Transgenic Mice With Cardiomyocyte-Specific Overexpression of Protein Phosphatase 2C

• Main Authors: Paula Bollmann (Author), Franziska Werner (Author), Marko Jaron (Author), Tom A. Bruns (Author), Hartmut Wache (Author), Jochen Runte (Author), Peter Boknik (Author), Uwe Kirchhefer (Author), Frank U. Müller (Author), Igor B. Buchwalow (Author), Sven Rothemund (Author), Joachim Neumann (Author), Ulrich Gergs (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As part of our ongoing studies on the potential pathophysiological role of serine/threonine phosphatases (PP) in the mammalian heart, we have generated mice with cardiac-specific overexpression of PP2Cβ (PP2C-TG) and compared them with littermate wild type mice (WT) serving as a control. Cardiac fib...