New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies

• Asıl Yazarlar: Romina A. Guedes (Yazar), Jorge H. Grilo (Yazar), Andreia N. Carvalho (Yazar), Pedro M. P. Fernandes (Yazar), Ana S. Ressurreição (Yazar), Vanessa Brito (Yazar), Adriana O. Santos (Yazar), Samuel Silvestre (Yazar), Eleonora Gallerani (Yazar), Maria João Gama (Yazar), Riccardo Gavioli (Yazar), Jorge A. R. Salvador (Yazar), Rita C. Guedes (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Cancer is a complex multifactorial disease whose pathophysiology involves multiple metabolic pathways, including the ubiquitin-proteasome system, for which several proteasome inhibitors have already been approved for clinical use. However, the resistance to existing therapies and the occurrence of s...