Epidemiology of Phenylketonuria Disease in Jordan: Medical and Nutritional Challenges

• Main Authors: Safwan Dababneh (Author), Mohammed Alsbou (Author), Nashat Taani (Author), Ghazi Sharkas (Author), Refqi Ismael (Author), Latifeh Maraqa (Author), Omar Nemri (Author), Hanin Al-Jawaldeh (Author), Nadeen Kopti (Author), Enas Atieh (Author), Arab Almasri (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Phenylketonuria (PKU) is the most frequent inborn error in amino acid metabolism caused by a deficiency of the phenylalanine hydroxylase enzyme (PAH). If PKU is left untreated, high concentrations of phenylalanine (Phe) accumulate in the blood, leading to severe brain dysfunction, neurod...