Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage

• Main Authors: Daria M. Monti (Author), Giuseppina De Simone (Author), Emma Langella (Author), Claudiu T. Supuran (Author), Anna Di Fiore (Author), Simona M. Monti (Author)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Carbonic anhydrases (CAs) III and VII are two cytosolic isoforms of the α-CA family which catalyze the physiological reaction of carbon dioxide hydration to bicarbonate and proton. Despite these two enzymes share a 49% sequence identity and present a very similar three-dimensional structure, they sh...