Genetic determination of the cellular basis of the ghrelin-dependent bone remodeling

• Main Authors: Chengshan Ma (Author), Toru Fukuda (Author), Hiroki Ochi (Author), Satoko Sunamura (Author), Cheng Xu (Author), Ren Xu (Author), Atsushi Okawa (Author), Shu Takeda (Author)
• Format: Book
• Published: Elsevier, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Bone mass is maintained through a balance of bone formation and resorption. This homeostatic balance is regulated by various systems involving humoral and local factors. The discovery that the anorexigenic hormone leptin regulates bone mass via neuronal pathways revealed that neurons and...