Upregulation of Intestinal NHE3 Following Saline Ingestion

• Main Authors: Venkanna Pasham (Author), Anand Rotte (Author), Shuchen Gu (Author), Wenting Yang (Author), Madhuri Bhandaru (Author), Rexhep Rexhepaj (Author), Ganesh Pathare (Author), Florian Lang (Author)
• Format: Book
• Published: Karger Publishers, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Little is known about the effect of salt content of ingested fluid on intestinal transport processes. Osmosensitive genes include the serum- and glucocorticoid-inducible kinase SGK1, which is up-regulated by hyperosmolarity and cell shrinkage. SGK1 is in turn a powerful stimulator of the...