Reduce susceptibility to cefiderocol in gram negative bacteria in children: Is hope already lost before it's even arrived?

• Main Authors: Chiara Russo (Author), Alessio Mesini (Author), Marcello Mariani (Author), Elisa Tavella (Author), Claudia Sette (Author), Elisabetta Ugolotti (Author), Claudia Bartalucci (Author), Candida Palmero (Author), Roberto Bandettini (Author), Elio Castagnola (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In last years the diffusion of carbapenem resistance in Gram-negative bacteria (CR-GNB) is increasing worldwide, mainly due to the expression of carbapenemases. Cefiderocol has molecular characteristics that ideally confers activity against all CR-GNB, but resistant strains have already...