Influence of Glucose on <i>Candida albicans</i> and the Relevance of the Complement FH-Binding Molecule Hgt1 in a Murine Model of Candidiasis

• Main Authors: Verena Harpf (Author), Samyr Kenno (Author), Günter Rambach (Author), Verena Fleischer (Author), Nadia Parth (Author), Christian X. Weichenberger (Author), Peter Garred (Author), Silke Huber (Author), Cornelia Lass-Flörl (Author), Cornelia Speth (Author), Reinhard Würzner (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Candidiasis is common in diabetic patients. Complement evasion is facilitated by binding complement factor H (FH). Since the expression of high-affinity glucose transporter 1 (Hgt1), a FH-binding molecule, is glucose-dependent, we aimed to study its relevance to the pathogenesis of <i>Candida...