Metformin: A promising clinical therapeutical approach for BPH treatment via inhibiting dysregulated steroid hormones-induced prostatic epithelial cells proliferation

• Main Authors: Tingting Yang (Author), Jiayu Yuan (Author), Yuting Peng (Author), Jiale Pang (Author), Zhen Qiu (Author), Shangxiu Chen (Author), Yuhan Huang (Author), Zhenzhou Jiang (Author), Yilin Fan (Author), Junjie Liu (Author), Tao Wang (Author), Xueyan Zhou (Author), Sitong Qian (Author), Jinfang Song (Author), Yi Xu (Author), Qian Lu (Author), Xiaoxing Yin (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The occurrence of benign prostate hyperplasia (BPH) was related to disrupted sex steroid hormones, and metformin (Met) had a clinical response to sex steroid hormone-related gynaecological disease. However, whether Met exerts an antiproliferative effect on BPH via sex steroid hormones remains unclea...