Protective effect of compatible herbs in Jin-Gu-Lian formula against Alangium chinense-induced neurotoxicity via oxidative stress, neurotransmitter metabolisms, and pharmacokinetics

• Main Authors: Dongyin Lian (Author), Tengfei Chen (Author), Lihua Yan (Author), Hongping Hou (Author), Shuangrong Gao (Author), Qin Hu (Author), Guangping Zhang (Author), Han Li (Author), Ling Song (Author), Yunhang Gao (Author), Yunxi Pu (Author), Ying Chen (Author), Bo Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:A. chinense frequently used in Miao medicine to treat rheumatic diseases. However, as a famous toxic herb, Alangium chinense and its representative components exhibit ineluctable neurotoxicity, thus creating significant challenges for clinical application. The combined application with co...