Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2

• Main Authors: Rui Su (Author), Weiwei Cao (Author), Guoxu Ma (Author), Weiping Li (Author), Zongyang Li (Author), Yongpei Liu (Author), Lei Chen (Author), Zebin Chen (Author), Xuejuan Li (Author), Ping Cui (Author), Guodong Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Due to its highly aggressiveness and malignancy, glioblastoma (GBM) urgently requires a safe and effective treatment strategy. Zeylenone, a natural polyoxygenated cyclohexenes compound isolated from Uvaria grandiflora, has exhibited potential biological activities in various human dise...