The effect of dissolution medium, rotation speed and compaction pressure on the intrinsic dissolution rate of amlodipine besylate, using the rotating disk method

The aim of this study was to evaluate the effect of dissolution medium, rotation speed and compaction pressure on the intrinsic dissolution rate (IDR) of the antihypertensive drug amlodipine besylate, using the rotating disk method. Accordingly, a fractional factorial design (33-1) was used, employi...

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Autors principals: Leandro Giorgetti (Autor), Michele Georges Issa (Autor), Humberto Gomes Ferraz (Autor)
Format: Llibre
Publicat: Universidade de São Paulo, 2014-09-01T00:00:00Z.
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