Fabrication of an In Situ pH-Responsive Raloxifene-Loaded Invasome Hydrogel for Breast Cancer Management: In Vitro and In Vivo Evaluation

• Main Authors: Hanan O. Farouk (Author), Marwa M. Nagib (Author), Amr Gamal Fouad (Author), Demiana M. Naguib (Author), Sherif Faysal Abdelfattah Khalil (Author), Amany Belal (Author), Samar F. Miski (Author), Nisreen Khalid Aref Albezrah (Author), Shatha Hallal Al-Ziyadi (Author), Gi-Hui Kim (Author), Ahmed H. E. Hassan (Author), Kyung-Tae Lee (Author), Doaa S. Hamad (Author)
• Format: Book
• Published: MDPI AG, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Objectives: Raloxifene (RLF) is a therapeutic option for invasive breast cancer because it blocks estrogen receptors selectively. Low solubility, limited targeting, first-pass action, and poor absorption are some of the challenges that make RLF in oral form less effective. This study aime...