Naringenin nanocrystals for improving anti-rheumatoid arthritis activity

• Main Authors: Guangshuai Zhang (Author), Guangyuan Sun (Author), Haishan Guan (Author), Mo Li (Author), Yanhua Liu (Author), Baocheng Tian (Author), Zhonggui He (Author), Qiang Fu (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Naringenin (NAR) is recognized for its anti-inflammatory activity. However, the clinical application of NAR is limited by low bioavailability, which is attributed to its poor aqueous solubility. In this study, we aimed to improve the therapeutic efficacy of NAR by formulating it into nanocrystals (N...