Necrotizing enterocolitis: a potential protective role for intestinal alkaline phosphatase as lipopolysaccharide detoxifying enzyme

IntroductionNecrotizing enterocolitis (NEC) is a life-threatening inflammatory disease. Its onset might be triggered by Toll-Like Receptor 4 (TLR4) activation via bacterial lipopolysaccharide (LPS). We hypothesize that a deficiency of intestinal alkaline phosphatase (IAP), an enzyme secreted by ente...

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Bibliographic Details
Main Authors: Raquel Dos Santos Martins (Author), Jan B. F. Hulscher (Author), Albert Timmer (Author), Elisabeth M. W. Kooi (Author), Klaas Poelstra (Author)
Format: Book
Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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