Design, synthesis, and biological evaluation of benzoheterocyclic sulfoxide derivatives as quorum sensing inhibitors in Pseudomonas aeruginosa

• Główni autorzy: Shen Mao (Autor), Qiaoqiang Li (Autor), Zhikun Yang (Autor), Yasheng Li (Autor), Xinyi Ye (Autor), Hong Wang (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Six series of benzoheterocyclic sulfoxide derivatives were designed and synthesised as Pseudomonas aeruginosa (P. aeruginosa) quorum sensing inhibitors in this paper. We experimentally demonstrated that 6b significantly inhibited the formation of P. aeruginosa PAO1 biofilm without affecting the grow...