Targeted delivery of RNAi to cancer cells using RNA-ligand displaying exosome

• Main Authors: Nasir Uddin (Author), Daniel W. Binzel (Author), Dan Shu (Author), Tian-Min Fu (Author), Peixuan Guo (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exosome is an excellent vesicle for in vivo delivery of therapeutics, including RNAi and chemical drugs. The extremely high efficiency in cancer regression can partly be attributed to its fusion mechanism in delivering therapeutics to cytosol without endosome trapping. However, being composed of a l...