The effect of the source and the concentration of polymers on the release of chlorhexidine from mucoadhesive buccal tablets

• Principais autores: Enas Al-Ani (Autor), Claire Martin (Autor), Stephen T. Britland (Autor), Khalid Doudin (Autor), David J. Hill (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2019-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

In the current work, two groups of chlorhexidine mucoadhesive buccal tablets were prepared, using either rod or irregularly-shaped spherical particles of hydroxypropyl methylcellulose and different ratios of poloxamer 407 (P407). The tablets were designed to release the drug over two hours. Their ph...