Peripheral Blood-Derived Mesenchymal Stem Cells Modulate Macrophage Plasticity through the IL-10/STAT3 Pathway

• Main Authors: Qi-Ming Pang (Author), Rui Yang (Author), Meng Zhang (Author), Wang-Hui Zou (Author), Nan-Nan Qian (Author), Qi-Jing Xu (Author), Hui Chen (Author), Jia-Chen Peng (Author), Xiao-Ping Luo (Author), Qian Zhang (Author), Tao Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSCs) are multipotent cells that can skew the balance of M1/M2 macrophage polarization towards the M2 phenotype via their paracrine effects, thereby promoting anatomical and functional recovery after many inflammatory diseases induced by macrophages. However, the underlying m...