Influence of quercetin and chrysin on the intestinal permeability of paclitaxel, a substrate of P-glycoprotein and CYP3A4 using in vitro rat gut sacs
P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4) play a significant role in the disposition and elimination of drugs. The objective of this study was to investigate the mechanism underlying the interaction between paclitaxel (substrate of P-gp and CYP3A4) and quercetin and chrysin (known modul...
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Format: | Book |
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Shiraz University of Medical Sciences,
2019-09-01T00:00:00Z.
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A1234.567 |
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