Chimpanzee adenoviral vectors as vaccines - challenges to move the technology into the fast lane

• Autori principali: Alessandra Vitelli (Autore), Antonella Folgori (Autore), Elisa Scarselli (Autore), Stefano Colloca (Autore), Stefania Capone (Autore), Alfredo Nicosia (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2017-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Introduction: In recent years, replication-defective chimpanzee-derived adenoviruses have been extensively evaluated as genetic vaccines. These vectors share desirable properties with human adenoviruses like the broad tissue tropism and the ease of large-scale manufacturing. Additionally, chimpanzee...