Chimpanzee adenoviral vectors as vaccines - challenges to move the technology into the fast lane

• Main Authors: Alessandra Vitelli (Author), Antonella Folgori (Author), Elisa Scarselli (Author), Stefano Colloca (Author), Stefania Capone (Author), Alfredo Nicosia (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: In recent years, replication-defective chimpanzee-derived adenoviruses have been extensively evaluated as genetic vaccines. These vectors share desirable properties with human adenoviruses like the broad tissue tropism and the ease of large-scale manufacturing. Additionally, chimpanzee...