A simple and safe antibody neutralization assay based on polio pseudoviruses

• Main Authors: Zheng Jiang (Author), Guixiu Liu (Author), Liao Guo-yang (Author), Mingbo Sun (Author), Kangwei Xu (Author), Zhifang Ying (Author), Jianfeng Wang (Author), Xuguang Li (Author), Changgui Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The evaluation of the immunogenicity of Sabin strain based Inactivated Poliovirus Vaccines (sIPV) necessitates the use of wild strains in neutralization assays to assess the potential cross-reactivity of antibodies. The live virus strains including wild and Sabin strains must be handled in level 3 b...