Reverse phase high-performance liquid chromatography for quantification of hydroxymethylnitrofurazone in polymeric nanoparticles

• Main Authors: Lis Marie Monteiro (Author), Guilherme Diniz Tavares (Author), Elizabeth Igne Ferreira (Author), Vladi Olga Consiglieri (Author), Nadia Araci Bou-Chacra (Author), Raimar Löbenberg (Author)
• Format: Book
• Published: Universidade de São Paulo, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hydroxymethylnitrofurazone (NFOH) is a new compound with potential leishmanicidal and trypanocidal activity. Despite its effectiveness, the formulators have to overcome its poor aqueous solubility. Recently, polymeric nano-scale drug delivery systems have proposed for the treatment of neglected dise...