Systematic evaluation of irinotecan-induced intestinal mucositis based on metabolomics analysis

• Hoofdauteurs: Qing-Qing Yu (Auteur), Heng Zhang (Auteur), Shiyuan Zhao (Auteur), Dadi Xie (Auteur), Haibo Zhao (Auteur), Weidong Chen (Auteur), Min Pang (Auteur), Baoqin Han (Auteur), Pei Jiang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Chemotherapy-induced intestinal mucositis (CIM) is a major dose-limiting side effect of chemotherapy, especially in regimens containing irinotecan (CPT-11). Several studies on the pathologic mechanisms of CIM focused on both the genomics and molecular pathways triggered by chemotherapy. However, sys...