Systematic evaluation of irinotecan-induced intestinal mucositis based on metabolomics analysis

• Main Authors: Qing-Qing Yu (Author), Heng Zhang (Author), Shiyuan Zhao (Author), Dadi Xie (Author), Haibo Zhao (Author), Weidong Chen (Author), Min Pang (Author), Baoqin Han (Author), Pei Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemotherapy-induced intestinal mucositis (CIM) is a major dose-limiting side effect of chemotherapy, especially in regimens containing irinotecan (CPT-11). Several studies on the pathologic mechanisms of CIM focused on both the genomics and molecular pathways triggered by chemotherapy. However, sys...