Systematic evaluation of irinotecan-induced intestinal mucositis based on metabolomics analysis

• Үндсэн зохиолчид: Qing-Qing Yu (Зохиогч), Heng Zhang (Зохиогч), Shiyuan Zhao (Зохиогч), Dadi Xie (Зохиогч), Haibo Zhao (Зохиогч), Weidong Chen (Зохиогч), Min Pang (Зохиогч), Baoqin Han (Зохиогч), Pei Jiang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Chemotherapy-induced intestinal mucositis (CIM) is a major dose-limiting side effect of chemotherapy, especially in regimens containing irinotecan (CPT-11). Several studies on the pathologic mechanisms of CIM focused on both the genomics and molecular pathways triggered by chemotherapy. However, sys...