Inhibition of Lipid Accumulation in Skeletal Muscle and Liver Cells: A Protective Mechanism of Bilirubin Against Diabetes Mellitus Type 2

• Main Authors: Claudia A. Hana (Author), Eva-Maria Klebermass (Author), Theresa Balber (Author), Markus Mitterhauser (Author), Ruth Quint (Author), Yvonne Hirtl (Author), Antonia Klimpke (Author), Sophie Somloi (Author), Juliana Hutz (Author), Elisabeth Sperr (Author), Paulina Eder (Author), Jana Jašprová (Author), Petra Valášková (Author), Libor Vítek (Author), Elke Heiss (Author), Karl-Heinz Wagner (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ectopic lipid accumulation in skeletal muscle and liver drives the pathogenesis of diabetes mellitus type 2 (DMT2). Mild hyperbilirubinaemia has been repeatedly suggested to play a role in the prevention of DMT2 and is known for its capacity to shape an improved lipid phenotype in humans and in anim...