Design and Pharmaceutical Evaluation of a Nano-Enabled Crosslinked Multipolymeric Scaffold for Prolonged Intracranial Release of Zidovudine

• Main Authors: Sheri-Lee Harilall (Author), Yahya E Choonara (Author), Girish Modi (Author), Lomas K Tomar (Author), Charu Tyagi (Author), Pradeep Kumar (Author), Lisa C du Toit (Author), Sunny E Iyuke (Author), Michael P Danckwerts (Author), Viness Pillay (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. Nanomedicine explores and allows for the development of drug delivery devices with superior drug uptake, controlled release and fewer drug side-effects. This study explored the use of nanosystems to formulate an implantable drug delivery device capable of sustained zidovudine release over a...