Pioglitazone-Mediated Attenuation of Experimental Colitis Relies on Cleaving of Annexin A1 Released by Macrophages

• Main Authors: Gustavo Henrique Oliveira da Rocha (Author), Marina de Paula-Silva (Author), Milena Fronza Broering (Author), Pablo Rhasan dos Santos Scharf (Author), Larissa Satiko Alcântara Sekimoto Matsuyama (Author), Silvya Stuchi Maria-Engler (Author), Sandra Helena Poliselli Farsky (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ulcerative colitis and Crohn's disease are chronic inflammatory bowel diseases (IBDs) which burden health systems worldwide; available pharmacological therapies are limited and cost-intensive. Use of peroxisome proliferator activated-receptor γ (PPARγ) ligands for IBD treatment, while promising...