Diagnosis of neurosyphilis with cerebrospinal fluid pcr: a systematic review

• Main Authors: Renan Barros Domingues (Author), Carlos Alberto Salzedas Giafferi (Author), Márcio Vega dos Santos (Author), Fernando Brunale Vilela de Moura Leite (Author), Carlos Senne (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Background Neurosyphilis is difficult to be diagnosed. CSF VDRL is the gold standard, but its sensitivity is low. Cerebrospinal fluid (CSF) PCR for the detection of Treponema pallidum DNA has been evaluated; however, its diagnostic value is still poorly understood. Methods Here we performed...