The Effects of a Single Oral Dose of Pyridoxine on Alpha-Aminoadipic Semialdehyde, Piperideine-6-Carboxylate, Pipecolic Acid, and Alpha-Aminoadipic Acid Levels in Pyridoxine-Dependent Epilepsy

• Main Authors: Junjuan Wang (Author), Jiao Xue (Author), Pan Gong (Author), Minhang Wu (Author), Wenshuang Yang (Author), Shiju Jiang (Author), Ye Wu (Author), Yuwu Jiang (Author), Yuehua Zhang (Author), Tatiana Yuzyuk (Author), Hong Li (Author), Zhixian Yang (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Purpose: To evaluate the effects of a single oral dose of pyridoxine on lysine metabolites including α-aminoadipic semialdehyde (a-AASA), piperideine-6-carboxylate (P6C), the sum of AASA and P6C (AASA-P6C), pipecolic acid (PA), and α-aminoadipic acid (α-AAA) in PDE patients.Methods: The lysine metab...