Acquired Concurrent EGFR T790M and Driver Gene Resistance From EGFR-TKIs Hampered Osimertinib Efficacy in Advanced Lung Adenocarcinoma: Case Reports

The acquired resistance of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) is inevitable and heterogeneous. The strategies to overcome acquired resistance are significant. For patients with secondary T790M-positive after early generation EGFR-TKIs, osimertinib is the standard...

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Main Authors: Yue Zeng (Author), Yuanqing Feng (Author), Guihua Fu (Author), Junlan Jiang (Author), Xiaohan Liu (Author), Yue Pan (Author), Chunhong Hu (Author), Xianling Liu (Author), Fang Wu (Author)
Formato: Livro
Publicado em: Frontiers Media S.A., 2022-04-01T00:00:00Z.
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