Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With α-Alkyl Moieties

• Главные авторы: Narakorn Khunweeraphong (Автор), Shushi Nagamori (Автор), Pattama Wiriyasermkul (Автор), Yumiko Nishinaka (Автор), Printip Wongthai (Автор), Ryuichi Ohgaki (Автор), Hidekazu Tanaka (Автор), Hideyuki Tominaga (Автор), Hiroyuki Sakurai (Автор), Yoshikatsu Kanai (Автор)
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• Опубликовано: Elsevier, 2012-01-01T00:00:00Z.
• Предметы: article
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System L is a major transport system for cellular uptake of neutral amino acids. Among system L transporters, L-type amino acid transporter 1 (LAT1) is responsible for the nutrient uptake in cancer cells, whereas L-type amino acid transporter 2 (LAT2) is a transporter for non-cancer cells. In this s...