Physiologically Based Pharmacokinetic Modeling in Pregnant Women Suggests Minor Decrease in Maternal Exposure to Olanzapine

Pregnancy is accompanied by significant physiological changes that might affect the in vivo drug disposition. Olanzapine is prescribed to pregnant women with schizophrenia, while its pharmacokinetics during pregnancy remains unclear. This study aimed to develop a physiologically based pharmacokineti...

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Main Authors: Liang Zheng (Author), Hongyi Yang (Author), André Dallmann (Author), Xuehua Jiang (Author), Ling Wang (Author), Wei Hu (Author)
Format: Book
Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
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