Physiologically Based Pharmacokinetic Modeling in Pregnant Women Suggests Minor Decrease in Maternal Exposure to Olanzapine
Pregnancy is accompanied by significant physiological changes that might affect the in vivo drug disposition. Olanzapine is prescribed to pregnant women with schizophrenia, while its pharmacokinetics during pregnancy remains unclear. This study aimed to develop a physiologically based pharmacokineti...
Saved in:
Main Authors: | Liang Zheng (Author), Hongyi Yang (Author), André Dallmann (Author), Xuehua Jiang (Author), Ling Wang (Author), Wei Hu (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2022-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Physiologically‐Based Pharmacokinetic Modeling for Predicting Drug Interactions of a Combination of Olanzapine and Samidorphan
by: Lei Sun, et al.
Published: (2020) -
Using physiologically‐based pharmacokinetic modeling for predicting the effects of hepatic impairment on the pharmacokinetics of olanzapine and samidorphan given as a combination tablet
by: Lei Sun, et al.
Published: (2021) -
Application of Physiologically Based Pharmacokinetic Modeling to Predict Maternal Pharmacokinetics and Fetal Exposure to Oxcarbazepine
by: Lixia He, et al.
Published: (2022) -
Physiologically‐based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID‐19
by: Xiaomei I. Liu, et al.
Published: (2023) -
Physiologically Based Pharmacokinetic Modeling in Pregnancy, during Lactation and in Neonates: Achievements, Challenges and Future Directions
by: Karel Allegaert, et al.
Published: (2024)