Li-Fraumeni syndrome in Tunisian carriers with different and rare tumor phenotype: genotype-phenotype correlation

• Main Authors: Hela Sassi (Author), Rym Meddeb (Author), Mohamed Aziz Cherif (Author), Chiraz Nasr (Author), Aouatef Riahi (Author), Samia Hannachi (Author), Neila Belguith (Author), Ridha M'rad (Author)
• 格式: 图书
• 出版: BMC, 2022-03-01T00:00:00Z.
• 主题: article
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Abstract Background Li-Fraumeni syndrome (LFS) is a rare autosomal hereditary predisposition to multiples cancers, mainly affecting young individuals. It is characterized by a broad tumor spectrum. To our best knowledge, only one Tunisian study with a confirmed LFS was published. Methods Our study f...