THE EFFECT OF HPMC AS A GEL BASE AND TWEEN 80 SPAN 80 COMBINATIONS AS EMULGATORS IN ACETOSAL TRANSDERMAL EMULGEL PREPARATIONS

• Egile Nagusiak: Nirwati Rusli (Egilea), Muhammad Azdar Setiawan (Egilea), Nur Hikmawati (Egilea)
• Formatua: Liburua
• Argitaratua: Universitas Muhammadiyah Magelang, 2022-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Acetosal or acetyl salicylic acid is a drug that has efficacy as ananalgesic, antipireic, and antiplatelet. Aacetosal undegoes cross-first metabolisism (first pass effect) causing low drug bioavailability. The smal lsolubility of acetosal will affect the rate of absorption which later affect the int...