Everolimus pharmacokinetics and exposure-response relationship in Japanese patients with advanced breast cancer

• المؤلفون الرئيسيون: Masaki Hirabatake (مؤلف), Tomoyuki Mizuno (مؤلف), Hironori Kato (مؤلف), Tohru Hashida (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Background: Everolimus is one of the key drugs for the treatment of advanced breast cancer. The optimal target concentration range for everolimus therapy in patients with breast cancer has not yet been established. This study aimed to characterize everolimus pharmacokinetics (PK) and determine the r...