The use of systemic medications in pediatric dermatoses: A review

Research has begun to illustrate a favorable efficacy and side-effect profile for many systemic agents used in pediatric dermatological conditions (i.e. atopic dermatitis, psoriasis, scleroderma, alopecia areata, chronic spontaneous urticaria, autoimmune blistering disorders, and hidradenitis suppur...

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Asıl Yazarlar: Shanthi Narla (Yazar), Githa Rahmayunita (Yazar), Rinadewi Astriningrum (Yazar), Tor Shwayder (Yazar), Ariyati Yosi (Yazar), Henry W. Lim (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Universitas Indonesia, 2019-12-01T00:00:00Z.
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Özet:Research has begun to illustrate a favorable efficacy and side-effect profile for many systemic agents used in pediatric dermatological conditions (i.e. atopic dermatitis, psoriasis, scleroderma, alopecia areata, chronic spontaneous urticaria, autoimmune blistering disorders, and hidradenitis suppurativa) despite not having extensive randomized clinical trials. The purpose of this article is to summarize the available data on the treatment regiments, safety, and efficacy of systemic immunosuppressants, including the newer biologics, focusing on the most up-to-date systematic reviews or randomized clinical trials. The review demonstrates that many of the present studies lack data on long-term efficacy and consist of small patient populations. Further research into the long-term safety of these systemic medications is of vital importance especially due to the chronic nature of most pediatric dermatological conditions that require the use of systemic agents.
Diğer Bilgileri:10.19100/jdvi.v4i1.189
2460-7991
2460-7991