Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin

Camptothecin (CPT) exhibits a number of challenges for its oral administration, including a low aqueous solubility, a lactone ring susceptible to hydrolysis, and an affinity to the intestinal P-gp. The aim of this work was to evaluate nanoparticles from Gantrez-based conjugates as carriers for the o...

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Main Authors: Judit Huarte (Author), Socorro Espuelas (Author), Cristina Martínez-Oharriz (Author), Juan M. Irache (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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