Machine Learning Predicts Drug Metabolism and Bioaccumulation by Intestinal Microbiota

• Main Authors: Laura E. McCoubrey (Author), Stavriani Thomaidou (Author), Moe Elbadawi (Author), Simon Gaisford (Author), Mine Orlu (Author), Abdul W. Basit (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over 150 drugs are currently recognised as being susceptible to metabolism or bioaccumulation (together described as depletion) by gastrointestinal microorganisms; however, the true number is likely higher. Microbial drug depletion is often variable between and within individuals, depending on their...