Cell Cycle Arrest and Apoptosis Induction by a New 2,4-Dinitrobenzenesulfonamide Derivative In Acute Leukemia Cells

• Main Authors: Patricia Alves Almeida (Author), Luiz Felipe Schmitz de Souza (Author), Mariana Franzoni Maioral (Author), Laura Otto Walter (Author), Bruna Fischer Duarte (Author), Íris Mattos Santos-Pirath (Author), Douglas Bauer Speer (Author), Larissa Sens (Author), Tiago Tizziani (Author), Aldo Sena de Oliveira (Author), Ricardo José Nunes (Author), Maria Cláudia Santos-Silva (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Current therapies for acute leukemias (ALs) are associated with severe adverse reactions and high relapse rates, which makes the search for new antileukemic agents a necessity. Therefore, the aim of this study was to evaluate the effects of a new sulfonamide, S1, in AL cells K562 and Jur...