The ALDH2 rs671 polymorphism is associated with athletic status and muscle strength in a Japanese population

• Main Authors: Naoki Kikuchi (Author), Takafumi Tajima (Author), Yuki Tamura (Author), Yoshiaki Yamanaka (Author), Kunitaka Menuki (Author), Takanobu Okamoto (Author), Mikako Sakamaki-Sunaga (Author), Akinori Sakai (Author), Kenji Hiranuma (Author), Koichi Nakazato (Author)
• Format: Book
• Published: Termedia Publishing House, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aldehyde dehydrogenase 2 (ALDH2) catalyses aldehyde species, including alcohol metabolites, mainly in the liver. We recently observed that ALDH2 is also expressed in skeletal muscle mitochondria; thus, we hypothesize that rs671 polymorphism-promoted functional loss of ALDH2 may induce deleterious ef...