Differential Effects of Cyclosporin A and Tacrolimus on Magnesium Influx in Caco2 Cells
PURPOSE: Hypomagnesemia with urinary magnesium (Mg) wasting is a well acknowledged side effect of cyclosporin A (CsA) and tacrolimus (FK506) treatments. TRPM6, TRPM7 and MagT1 are involved in the active transcellular Mg transport processes in intestine and kidney. Since Mg homeostasis is tightly con...
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Frontiers Media S.A.,
2012-06-01T00:00:00Z.
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