Novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of Alzheimer's disease

In this study, a series of potential ligands for the treatment of AD were synthesised and characterised as novel harmine derivatives modified at position 9 with benzyl piperazinyl. In vitro studies revealed that the majority of the derivatives exhibited moderate to potent inhibition against hAChE an...

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Bibliographic Details
Main Authors: Hongtao Du (Author), Jinzhi Song (Author), Fang Ma (Author), Hongxin Gao (Author), Xinyan Zhao (Author), Renjun Mao (Author), Xiaolong He (Author), Yan Yan (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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