The thermo-sensitive gene expression signatures of spermatogenesis

• Main Authors: Santosh K. Yadav (Author), Aastha Pandey (Author), Lokesh Kumar (Author), Archana Devi (Author), Bhavana Kushwaha (Author), Rahul Vishvkarma (Author), Jagdamba P. Maikhuri (Author), Singh Rajender (Author), Gopal Gupta (Author)
• Format: Book
• Published: BMC, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Spermatogenesis in most mammals (including human and rat) occurs at ~ 3 °C lower than body temperature in a scrotum and fails rapidly at 37 °C inside the abdomen. The present study investigates the heat-sensitive transcriptome and miRNAs in the most vulnerable germ cells (spermat...