Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria

• Main Authors: Juliana O. de Souza (Author), Suzete M. Almeida (Author), Guilherme E. Souza (Author), Camila L. Zanini (Author), Everton M. da Silva (Author), Juliana Calit (Author), Daniel Y. Bargieri (Author), Kangsa Amporndanai (Author), Svetlana Antonyuk (Author), S. Samar Hasnain (Author), Fabio C. Cruz (Author), Dhelio B. Pereira (Author), Glaucius Oliva (Author), Arlene G. Corrêa (Author), Anna C.C. Aguiar (Author), Rafael V.C. Guido (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

4(1H)-quinolone is an attractive template for antimalarial drug discovery campaigns. Given the current global increase in drug and insecticide resistance, the discovery of new antimalarial drugs is an urgent goal for the fight against malaria. Here, the synthesis and antiplasmodial profiling of a se...