Linarin ameliorates innate inflammatory response in an experimental dry eye model via modulation of the NLRP3 inflammasome

• Autors principals: Chen Mei (Autor), Li Jie (Autor), Peng Jun (Autor), Huang Yu (Autor), Ouyang Weijie (Autor), Liu Xiaoqing (Autor), Shen Zhibin (Autor), Li Changdong (Autor), Wang Yi (Autor), Peng Qinghua (Autor)
• Format: Llibre
• Publicat: KeAi Communications Co., Ltd., 2021-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Objective: To investigate the effect and mechanism of linarin (LA) in an experimental dry eye model Methods: LA or vehicle was applied in two dry eye models: an in vitro hyperosmotic stress model and an in vivo desiccating stress (DS) murine model. The viability of human corneal epithelial cells (HC...