Linarin ameliorates innate inflammatory response in an experimental dry eye model via modulation of the NLRP3 inflammasome

• Main Authors: Chen Mei (Author), Li Jie (Author), Peng Jun (Author), Huang Yu (Author), Ouyang Weijie (Author), Liu Xiaoqing (Author), Shen Zhibin (Author), Li Changdong (Author), Wang Yi (Author), Peng Qinghua (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To investigate the effect and mechanism of linarin (LA) in an experimental dry eye model Methods: LA or vehicle was applied in two dry eye models: an in vitro hyperosmotic stress model and an in vivo desiccating stress (DS) murine model. The viability of human corneal epithelial cells (HC...