The Use of Trichostatin A during Pluripotent Stem Cell Generation Does Not Affect MHC Expression Level

• Main Authors: Sara Farahi (Author), Sara Hosseini (Author), Hossein Ghanbarian (Author), Seyed Mahmoud Hashemi (Author), Mohammad Salehi (Author), Samaneh Hosseini (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pluripotent stem cells (PSCs) are considered as a potent tool for use in regenerative medicine. Highly efficient generation of PSCs through chromatin modulators such as trichostatin A (TSA) might change their MHC molecule expression profile. The efficiency of PSC generation and their immunogenicity...